Researchers from China and Nottingham have identified mutational changes occurring in a subtype of avian flu virus endemic in poultry farms in China. These alterations could increase the likelihood of transmission to humans. Researchers also say that the findings raise concerns of a potential epi
A study by researchers in China and Nottingham found that a subtype of the H3N8 avian influenza virus currently prevalent in Chinese poultry farms is undergoing mutations that facilitate airborne transmission and can cause severe infections in humans, raising fears of a potential pandemic. The research emphasizes the urgent need for close monitoring and research on these viruses in poultry and humans, noting that even vaccinated populations may be vulnerable to this new strain.
Researchers also say that the findings raise concerns of a potential epidemic or pandemic in the making and that concerted research is necessary to closely monitor such viruses in poultry and humans., report on the characterization of a human isolate – from a human patient – of the H3N8 avian influenza virus .
In humans, the avian H3N8 virus infection has been found to cause acute respiratory distress syndrome and can even be fatal. The virus is widespread in chicken flocks; however previously, the features of how it might be transmitted from animals to humans is poorly understood. “We demonstrate that an avian H3N8 virus isolated from a patient with severe pneumonia replicated efficiently in human bronchial and lung epithelial cells was extremely harmful in its effects in laboratory mammalian hosts and could be passed on through respiratory droplets,” says Professor Kin-Chow Chang,
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