Adolescents With Vitiligo Achieve Higher Repigmentation Rates With Topical Ruxolitinib Than Adults

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Adolescents With Vitiligo Achieve Higher Repigmentation Rates With Topical Ruxolitinib Than Adults
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The findings come from a post hoc analysis of data from two pivotal trials.

, 1.5% cream were more likely than adults to achieve complete repigmentation, a post hoc analysis of pivotal clinical trial data showed.

Compared with adults, a greater proportion of adolescents achieved F-VASI100 at week 24 , but there were no differences between the two groups at week 52 . Response rates were greater among adolescents vs adults for T-VASI75 at weeks 24 and 52 , as well as T-VASI90 at weeks 24 and 52 . "Adolescents repigmented more rapidly than adults, so that at 24 weeks, more teens had complete facial repigmentation and T-VASI75 and T-VASI90 results," Rosmarin said."With continued use of ruxolitinib cream, both more adults and adolescents achieved greater repigmentation.

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