Dr Anne Peters discusses recent data highlighting progress in managing type 1 diabetes.
, where stem cell-derived islet cells were given to individuals with type 1 diabetes and followed for a year. They reported on 12 participants, and basically, these little islet cells worked.
The next study that my patients and I found interesting came from the Barbara Davis Center and was done by Dr Halis Akturk and his colleagues. It was looking at the use ofwho wish to try combination therapy off-label with semaglutide, but this is the first randomized controlled trial to show the benefit.. It was a double-blind study. This was a 26-week placebo-controlled study, and they enrolled 72 individuals with type 1 diabetes from four US clinics.
In terms of secondary outcomes, there was a reduction in A1c by 0.7% in the semaglutide group compared to 0.3% in the placebo group. Time in range improved. People lost, on average, 18 lb, and there was a reduction in total daily insulin dose. There was noThis was really proof of concept, which I think all of us who treat many people with type 1 diabetes and have been using incretin therapy have shown to be beneficial.
Diabetes Mellitus Type I Type 1 Diabetes Type 1 DM T1DM T1D Type 1 Diabetes Mellitus Type 1 Diabetes Mellitus (T1DM) Immunocompromise Immunocompromised Immunosuppression Weight Loss Hypoglycemia Incretin Hormones Incretins Fellowship Fellows Obesity Obese Residency Residents Weight Management Adverse Effects Side Effects Body Mass Index BMI
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