New research suggests a 'tailored vaccine' might hold the key to treating bacteria-driven flares of eczema in children.
New research suggests a 'tailored vaccine' might hold the key to treating bacteria-driven flares of eczema in children. The team has taken several leaps forward in understanding how the immune response works in cases of eczema driven by the common, troublesome Staphylococcus aureus bacterium, and in doing so they have identified new cellular targets for a vaccine.
Eczema, also known as atopic dermatitis, affects up to one in four children in Ireland. Common symptoms include itchy, dry skin, and -- when bacteria are involved -- weeping wounds that can progress to more severe infections and have a detrimental effect on the quality of life of patients and their families. Although very rare, life-threatening systemic infections such as septicaemia may arise.
Working with 93 children between 0 and 16, the researchers compared immune responses between 3 groups of patients: eczema and a confirmedThe key discovery was that the proportions of certain immune cells known as"T cells," as well as other biomarkers, varied considerably in the different groups. There are many different types of T cells in our bodies but they all play unique roles in our immune response, helping to regulate the way we respond to infections.
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