Researchers have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment of cancer.
They are like the architects of our body: messenger ribonucleic acids, or mRNA for short. They contain detailed blueprints for proteins, which are read and translated by their"colleagues," the ribosomes. We could not survive without the proteins in our bodies -- they control cell division, provide a strong immune system and make our cells resistant to external attack.
Crucially, this particular pathway only works when m6A is present in specific regions of the mRNA. In this way, m6A particularly"comments" on the blueprints for proteins involved in cell differentiation -- that is, whether a cell will exist as a nerve cell, muscle cell, skin cell or some other form. In addition to the Würzburg researchers, the Institute of Molecular Biology in Mainz and the Goethe University in Frankfurt are also involved in the study, which is funded by the German Research Foundation as part of the Collaborative Research Centre TRR 319"RMaP: RNA Modification and Processing."You Zhou, Miona Ćorović, Peter Hoch-Kraft, Nathalie Meiser, Mikhail Mesitov, Nadine Körtel, Hannah Back, Isabel S.
Human Biology Nervous System Lung Cancer Diseases And Conditions Lymphoma Sickle Cell Anemia Immune System
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