Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein modulators by specifically tailored active substances.
A promising target for new RNA therapeutics now accessible." ScienceDaily. ScienceDaily, 10 April 2024. <www.sciencedaily.com
Ribonucleic acids , which decode the genetic code stored in DNA and produce proteins, fold into diverse structures to govern fundamental biological processes in all life forms, including ... In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers have developed chemically modified guide RNAs for a CRISPR system that targets RNA ...
Biomedical scientists have developed a new RNA-sequencing method -- 'Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing,' or PANDORA-seq -- that can help discover numerous ... Cancer cells have evolved mechanisms to escape the body's immune defense. Agents that prevent immune escape are attractive targets for the development of new cancer therapies. Scientists have now ...Study Uses Artificial Intelligence to Show How Personality Influences the Expression of Our Genes
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Researchers reveal mechanism behind most common mammalian mRNA modificationRNA—in the form of messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA)—transforms the genome coded by DNA into proteins that form the backbone of all cellular functions. However, biochemical modifications to RNA frequently occur, with a subsequent influence on gene expression and the potential to cause disease.
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A promising target for new RNA therapeutics now accessibleOnly recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein modulators by specifically tailored active substances.
Read more »
Messenger RNAs with multiple 'tails' could lead to more effective therapeutics, say researchersMessenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, are also being developed as a new class of drugs.
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Bacterial RNAs have shorter lifetimes than expectedThe decay of ribonucleic acid (RNA) is a crucial mechanism for controlling gene expression in response to environmental stresses.
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Model suggests how ancient RNA may have gained self-cutting ability essential for lifeScientists have long pondered the beginnings of life on Earth. One theory is that RNA, which is ubiquitous across all domains of life, played a central role in early life. Similar to DNA, RNA possesses the ability to store genetic information.
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Gene Therapy, DNA's Past, RNA's Future: A Time Of PromiseI am a scientist, businessman, author, and philanthropist. For nearly two decades, I was a professor at Harvard Medical School and Harvard School of Public Health where I founded two academic research departments, the Division of Biochemical Pharmacology and the Division of Human Retrovirology.
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