A New Field of Computing Powered by Human Brain Cells: “Organoid Intelligence”

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A New Field of Computing Powered by Human Brain Cells: “Organoid Intelligence”
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Johns Hopkins researchers break ground on new field of ‘organoid intelligence’. According to researchers at Johns Hopkins University, a 'biocomputer' powered by human brain cells could be developed within our lifetime. This technology is expected to exponentially expand the capabilities of modern

Organoid intelligence is an emerging scientific field that seeks to create biocomputers by utilizing lab-grown brain organoids as “biological hardware.”According to researchers at

Magnified image of a brain organoid produced in Thomas Hartung’s lab, dyed to show neurons in magenta, cell nuclei in blue, and other supporting cells in red and green. Credit: Jesse Plotkin/Johns Hopkins University Hartung began to grow and assemble brain cells into functional organoids in 2012 using cells from human skin samples reprogrammed into an embryonic stem cell-like state. Each organoid contains about 50,000 cells, about the size of a fruit fly’s nervous system. He now envisions building a futuristic computer with such brain organoids.

“The brain is still unmatched by modern computers,” Hartung said. “Frontier, the latest supercomputer in Kentucky, is a $600 million, 6,800-square-feet installation. Only in June of last year, it exceeded for the first time the computational capacity of a single human brain — but using a million times more energy.”

Organoid intelligence could also revolutionize drug testing research for neurodevelopmental disorders and neurodegeneration, said Lena Smirnova, a Johns Hopkins assistant professor of environmental health and engineering who co-leads the investigations.

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