Using a mouse model, Japanese researchers unleash the likely mechanism of action of Actinidia arguta (sarunashi) juice on lung cancer development. Lung cancer is a leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rat
Japanese researchers showed that Actinidia arguta juice inhibits lung cancer in mice.
Using a mouse model, researchers from Okayama University led by Dr. Sakae Arimoto-Kobayashi, Associate Professor in the Faculty of Pharmaceutical Sciences, Okayama University, have shown that Sarunashi juice and its constituting component isoquercetin help prevent and reduce lung cancer.is one of the richest sources of polyphenols and vitamin C. Previously, the researchers had demonstrated the inhibitory effect of Sarunashi juice on mutagenesis, inflammation, and mouse skin tumorigenesis.
To this end, the team induced tumor growth in mice using NNK, a known cancer-causing compound present in tobacco products. Using a series of experiments and controls, the team studied the effects of sar-j and isoQ on lung tumorigenesis in mice.
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