A ketamine pill may help hard-to-treat depression with fewer side effects, early research suggests

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A ketamine pill may help hard-to-treat depression with fewer side effects, early research suggests
Ketamine PillTreatDepression
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A new ketamine pill may help hard-to-treat depression with fewer side effects than other forms of the treatment, early research suggests.

Video above: Psychologist explains new digital depression treatment, RejoynTechnically, no form of ketamine has been approved by the U.S. Food and Drug Administration to treat any psychiatric disorder, including depression. A derivative of ketamine, called esketamine, was approved in 2019 to treat depression. It's a nasal spray called Spravato. There's also FDA-approved injected ketamine, brand-named Ketalar, which can be prescribed off-label.

Researchers did see what's called a dose-response, however, meaning the higher the dose of the drug, the more relief participants had in their depressive symptoms, which is usually a sign that the drug is having a real effect.People who took the highest dose, 180 milligrams a day, did see a statistically significant benefit, a reduction in their depression score of about six points compared with the placebo group.

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