The search for a way to treat Alzheimer's disease has puzzled scientists for decades. This may be why some researchers are shifting their focus slightly, investigating whether treating the systems affected by Alzheimer's (as opposed to the causes) ma
To conduct their study, the researchers pooled together 19 studies, looking at data from a total of over 1,800 patients. They also looked at a number of different noradrenergic drugs, including those used to treat ADHD and depression.
They found that in the majority of studies, these drugs improved the overall thinking and understanding of people with Alzheimer's disease. However, they weren't shown to improve the performance of specific memory functions , executive functions , visuospatial abilities , or agitation., which is a common symptom of Alzheimer's. Apathy can greatly reduce quality of life and can advance loss of brain function.
Overall, this study suggests that noradrenergic drugs can be beneficial for some people with Alzheimer's disease, so long as the right dosage is used. However, caution should be taken when drawing conclusions, as this is not an experimental study – such as a randomized controlled trial, which would compare the effect of an intervention . There was also a lot of variation between the studies included in the review in how they were conducted and their results.
It's also worth noting that although these drugs were shown to have some benefit for brain function, they can come with a range of side effects. These include heart problems, addiction and, especially when misused, may result in
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