Researchers have discovered that an ingredient from the camu-camu berry, castalagin, changes the gut biome of mice, and may help fight cancer. Human trials are next
Polyphenols are “organic compounds found abundantly in plants, [which] have become an emerging field of interest in nutrition in recent decades.”“A growing body of research indicates that polyphenol consumption may play a vital role in health through the regulation of metabolism, weight, chronic disease, and cell proliferation.”
is “an inhibitory receptor that is expressed by all T cells during activation. It regulates T cell effector functions during various physiological responses, including acute and chronic infection, cancer and autoimmunity, and in immune homeostasis.”Cancer Discovery “Our results pave the way for clinical trials that will use castalagin as a complement to medications called immune checkpoint inhibitors in cancer patients,” adds Meriem Messaoudene, a postdoctoral student in Routy’s lab and first author of the study.
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