A Bold Gene-Editing Solution Began Testing—Then Hit the Strangest Twist

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A Bold Gene-Editing Solution Began Testing—Then Hit the Strangest Twist
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The medical breakthrough will have to wait a bit longer.

While gene-editing is the future of medicine, navigating a path toward that future is proving difficult. The Boston-based biotech firm Verve Therapeutics recently had to pause a clinical trial after a participating patient developed an unforeseen side effect to the gene-editing serum. The company says the unintended side effects actually stem from the drug's delivery system rather than the gene-editing process itself.

”In recent years, one of Verve’s biggest goals has been developing a gene-editing therapy that reduces cholesterol known to cause heart attacks for people suffering from hypercholesterolemia. While high-density lipoprotein cholesterol is sometimes referred to as the “good” kind of cholesterol, hypercholesterolemia deals in the latter, known as low-density lipoprotein .

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