A clinical trial has begun in South London to determine whether Ibuprofen is a viable treatment for patients hospitalized with COVID-19. The trial will use “lipid ibuprofen,” Details Here: AajNews
The trial will use “lipid ibuprofen,” which is different than the over-the-counter available ibuprofenThe LIBERATE Trial is a pioneering collaboration between London’s Guy’s & St Thomas’ NHS Foundation Trust, King’s College London, and the pharmaceutical organization the SEEK Group
The drug is being tested to assess whether it can prevent severe acute respiratory distress syndrome - a common complication of COVID-19- in patients suffering from novel coronavirus infection, and also to reduce the number of people needing treatment in intensive care unitsIbuprofen which is an anti-inflammatory and pain-relieving medicine is easily available OTC worldwide But this trial is using a special formulation of ibuprofen rather than the regular tabletsThe unique formulation of...
Scientists supervising the clinical trial hope that this lipid formulation, which dissolves ibuprofen into fat, will help keep hospitalized patients from requiring mechanical ventilation The trial will evaluate how three doses of the drug affect disease progression, length of critical care stay, and length of hospital stay Basically, the trial is done to determine whether the drug can reduce the degree of respiratory distress so that it can be managed in the hospital setting, without needing to...
Participants for the trial will be drawn from those who are hospitalized, but not so ill that they are in need of intensive care In this trial, half of the patients will receive standard care and the other half will receive standard care plus the unique ibuprofen formulationStudies in animals suggest that ibuprofen might treat acute respiratory distress syndrome One of the scientist at King’s College London, Prof Mitul Mehta said this about the trial:It’s noteworthy that ibuprofen was deemed to...
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