4,000 year-old plague DNA found in Britain may boost study of infectious diseases

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4,000 year-old plague DNA found in Britain may boost study of infectious diseases
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Scientists drilled into teeth and extracted dental pulp, which can trap DNA remnants of infectious diseases.

Working with local groups and the University of Oxford, the team took small skeletal samples from 34 individuals across the two sites.

They then drilled into teeth and extracted dental pulp, which can trap DNA remnants of infectious diseases. Author Pooja Swali, a PhD student at the FCI, said that being able to detect"ancient pathogens from degraded samples" from such a long time ago was"incredible". She added:"These genomes can inform us of the spread and evolutionary changes of pathogens in the past, and hopefully help us understand which genes may be important in the spread of infectious diseases.

"We see that this Yersinia pestis lineage, including genomes from this study, loses genes over time, a pattern that has emerged with later epidemics caused by the same pathogen."Previously, plague has been identified in several individuals from Eurasia between 5,000 and 2,500 years before present .

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