Researchers develop a microstructured 'artificial lung' model using bioprinting technology.
The COVID-19 pandemic has profoundly impacted our lives, claiming nearly 7.1 million lives globally. Scientists and medical professionals have been working tirelessly to understand the virus, its transmission pathways, and effective treatments. The urgency of developing vaccines and treatments has never been greater, prompting calls for Korea to expedite its drug development efforts to match those of developed countries.
In this study, researchers from POSTECH and the KRICT created a"3D artificial lung" using three-dimensional bioprinting technology. This advanced technology uses cells and biomaterials to produce lifelike tissues and organs, reducing the need for animal testing in fields such as regenerative medicine and drug discovery.
Moreover, the team perfectly recreated the pathways by which COVID-19 drugs reach the infected epithelial layer and inhibit virus replication. Unlike conventional 2D cell culture methods where drugs are directly administered to the epithelial cells, this study evaluated the drug efficacy after they crossed the tissue barrier through the artificial lung tissue.
The research was conducted with support from the Mid-Career Researcher Program of the National Research Foundation of Korea and the Korea Health Technology R&D Project of the Ministry of Health and Welfare.Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers have developed and validated a liquid biopsy that may help identify lung cancer ...
Lung Disease Lung Cancer Biotechnology Developmental Biology Biology Engineering Biochemistry Medical Technology
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