2024 NFL Week 2 odds, lines, spreads for all 16 games

Week 2 is nearly upon us. Check out the odds for all 16 matchups, beginning with Thursday's AFC East showdown between the Bills and Dolphins.

And just like that, Week 1 of the NFL season is nearly in the books — we've still got a huge Monday night showdown between the Jets and 49ers. After that, we're on to Week 2. Let's check out the lines for each NFL game at DraftKings Sportsbook, as the second week of the season is upon us. 2024 NFL Week 2 Odds THURSDAY, SEPT.

5 Moneyline: Commanders -142 favorites to win ; Giants +120 underdogs to win Total scoring Over/Under: 42 points scored by both teams combined LOS ANGELES CHARGERS @ CAROLINA PANTHERS Point spread: Chargers -5.5 Moneyline: Chargers -230 favorites to win ; Panthers +190 underdogs to win Total scoring Over/Under: 39.

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