2024 Breakthrough Prizes Announced: Cystic Fibrosis Pioneers Awarded $3 Million

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2024 Breakthrough Prizes Announced: Cystic Fibrosis Pioneers Awarded $3 Million
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Researchers at Vertex Pharmaceuticals were honored for their revolutionary work in the treatment of genetic disorder, along with other scientists in biology, physics and mathematics.

Researchers at Vertex Pharmaceuticals were honored for their revolutionary work in the treatment of the genetic disorder, along with other researchers in biology, physics and mathematics.1989, scientists first identified one of the genetic factors that can cause cystic fibrosis, a disorder that causes a progressive lung disease in children.

“There’s still more we need to do,” he says. “We’re working on more cystic fibrosis drugs that could be even better than Trikafta. We want to make sure we finish the job and ensure that all cystic fibrosis patients will have a therapy.” On Thursday, van Goor and two other Vertex researchers, Sabine Hadida and Paul Negulescu, won one of five $3 million Breakthrough Prizes for 2024, sharing the awards with 8 other scientists working in Fundamental Physics, Life Sciences and Mathematics. In addition, 15 early-career researchers were awarded $100,000 prizes for their contributions to physics and mathematics.

The money for the awards is provided by the Breakthrough Prize Foundation. The organization was founded by Yuri and Julia Milner, and the prizes were additionally cofounded by Facebook CEO Mark Zuckerberg and his wife, Priscilla Chan; Google cofounder Sergey Brin and 23andMe cofounder & CEO Anne Wojcicki. Over the past 12 years, the prizes have awarded $308 million to researchers in a variety of fields.

The other $3 million Life Sciences prize was awarded to Thomas Gasser, Ellen Sidransky and Andrew Singleton. The work of these researchers helped uncover the risk factors in the human genome that can lead to the development of Parkinson’s disease. Additionally, their work helped inform our current understanding of the disease, which is that it doesn’t have a single cause but rather, like cancer, is better thought of as a family of diseases that can be caused in different ways.

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