13 Best Peptide Creams 2024 to Smooth the Look of Fine Lines

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13 Best Peptide Creams 2024 to Smooth the Look of Fine Lines
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The best peptide creams help plump skin and smooth the look of fine lines. Shop top picks from dermatologists and editors to cap off your skin-care routines.

Peptides are multitasking chains of amino acids that are naturally occurring in the body, but within the best peptide creams, can be combined to do the absolute most for your skin—protecting its upper layer, ramping up collagen and elastin production, accelerating wound healing, and so much more. People usually look to peptides specifically, though, for their ability to smooth over fine lines. They've long been touted as a non-invasive, topical way to emulate injectable-like results.

It combines multiple peptides in one formula, including Matrixyl 3000 which many call 'Botox in a bottle.' There's also hyaluronic acid and glycerin involved, which boosts its hydration power.

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